Faculty: Joseph Basha, CCP John Ingram, CCP Matt Warhoover, CCP

0:00–Open
9:40–Delivery of Oxygen and Acute Renal Injury, Making the Connection – John Ingram, CCP
16:50–Acute Kidney injury – Incidence and diagnosis – What is acute kidney injury – Risk factors – Renal anatomy and physiology – Delivery of oxygen – Conduct of perfusion and alpha 1 vasoconstrictors – Post CPB renal failure mortality rate – The AKIN classification – Bun and creatine – The search of better biomarkers of AKI – Common AKI biomakers – Biomarkers by segment of the nephron injured
5:57–Acute kidney injury types and categories: – Risk factors pre-operative – peri-operative – post-operative
30:22–The nephron – the functional unit of the kidney
32:35–Nephron forms urine in three steps – Filtration – Re-absorption – Secretion
48:57–Renal Blood Flow
1:05:19–Delivery of oxygen and how is determined Cardiopulmonary Bypass; is our use of Phenylephrine Causing Acute Kidney Injury?–John Ingram, CCP
1:14:25–Oxygen delivery on bypass and hypo-tension increase acute kidney injury risk after cardiac operation
1:15:44–does our use of Phenylephrine on CPB play a role in post operative acute kidney injury
1:16:40–Phenylephrine prescribing information manufacturer’s insert
1:21:35–Phenylephrine’s renal vasoconstrictive action
1:29:00–evaluate the AKI risk factors 1:29:58 – pre-operative AKI risk factors
1:31:10–peri-operative AKI risk factors 1:32:07 – post-operative risk factors
1:34:39–ECMO economics – Matt Warhoover, CCP
1:39:26–ECMO initiation 1:44:50 – can CMS close it in the US?
1:49:21–Center for Medicare Services – reimbursement for ECMO
1:53:20–ECMO in adults in the US – impact and implications (outcome % of survived, hospital length of stay, ECMO days, respiratory support)
1:55:34–pushback from healthcare systems (centrally Cannulated, peripherally Cannulated, average total hospital charges)
1:57:49–updates to ECMO MS-DRG reimbursement (ECMO continuous, ECMO central, ECMO peripheral veno – arterial, ECMO Peripheral veno – venous)
2:00:39–Relevant MS-DRG reimbursement (assistance with cardiac output using Impeller pump, Intermittent, assistance with cardiac output using Impeller pump, continuous, other heart assist systems implant).
2:01:49–examples of professional and hospital billing and the resulting of reimbursement. ( central ECMO. respiratory system diagnosis with ventilator support, heart failure and shock with mcc or peripheral ECMO, cardiac arrest, unexplained with mcc or peripheral ECMO, septicemia or severe sepsis with mv).
2:04:12–Pushback from providers: – alternative cannulation strategies ( sport model, centralized venting, pVAD intersection) – alternative management strategies (Tracheostomy)
2:16:27–Discussion

Video: Concepts in ECMO Delivery of Oxygen and Acute Renal Injury, Making the Connection – Part 1